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Michael Obadia / Newsletter#7- article 2
- 26 oct. 2017
- 2 Min
N Acetyl cystéine : nouveau thrombolytique ?
Le N Acetyl cystéine bien connu pour ses propriétés mucolytiques pourrait être un traitement d’avenir dans les infarctus cérébraux. Une équipe INSERM du CHU de Caen montre à partir de différents modèles animaux des propriétés thrombolytiques intéressantes. *** Un thrombus artérielle est riche en plaquettes et facteur Von Willebrandt (FVW) qui forme un réseau reliés par des ponts disulfure entre cystéines. Le N Acetyl cystéine (NAC) connu pour ses propriétés mucolytiques par
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Michael Obadia / Newsletter#7- article 1
- 26 oct. 2017
- 3 Min
Fermeture du FOP : suite et fin ?
Le NEJM rapporte les résultats de 3 études dont l’étude française CLOSE coordonnée par JL MAS montrant le bénéfice à long terme de la fermeture du FOP (Foramen Ovale Perméable) associée aux antiagrégants dans les accidents ischémiques cérébraux d’étiologie indéterminée par rapport au traitement antiagrégant seul. Bien que le risque d’AVC soit faible sous traitement antiagrégant seul (moins de 6 % sur des périodes de suivi entre 3 et 6 ans) il semble logique de proposer la f
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